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Complex Regional Pain Syndrome (CRPS)

Additional Conditions

Complex Regional Pain Syndrome (CRPS)

A nervous system-driven condition producing severe, disproportionate pain, skin changes, and swelling in an affected limb.

2

Diagnoses

5

Treatments

2

FAQs

SCOPES

Non-Opioid

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Clinical Guide

Review this section for a concise clinical summary of the condition, including key causes, symptom patterns, and treatment pathways.

Clinical OverviewCondition DefinitionCommon CausesTypical SymptomsRelated DiagnosesSCOPES Clinical ApproachRecommended TreatmentsFrequently Asked Questions

Clinical Overview

CRPS is uncommon but highly disabling, with substantial long-term pain and function impact in many patients. (Source to be confirmed by SCOPES Health clinical team.)

Condition Definition

CRPS is a chronic pain condition, usually post-injury or post-surgery, where pain is disproportionate to the initial event and involves sensory, autonomic, and motor abnormalities.

Common Causes

Mechanisms involve dysregulation of sympathetic activity and central sensitization after injury, with persistent abnormal pain signaling and autonomic changes.

Typical Symptoms

Typical features include severe burning/throbbing pain, temperature/color changes, swelling, allodynia, sweating changes, and motor dysfunction in the affected limb.

Related Diagnoses

Allodynia

Pain from non-painful stimuli such as light touch or clothing.

Motor Dysfunction

Weakness, tremor, and impaired limb coordination in advanced or prolonged disease.

SCOPES Clinical Approach

SCOPES Health uses a multidisciplinary approach with early intervention. Sympathetic blocks, SCS, DRG stimulation, and PNS are selected based on presentation and limb distribution.

Recommended Treatments

  • Lumbar Sympathetic Blocks→
  • Stellate Ganglion Block (SGB)→
  • Spinal Cord Stimulation (SCS)→
  • Dorsal Root Ganglion (DRG) Stimulation→
  • Peripheral Nerve Stimulation (PNS)→

Frequently Asked Questions

How is CRPS diagnosed?

Diagnosis is clinical using Budapest Criteria, supported by testing to exclude other conditions when needed.

Is CRPS permanent?

Without treatment it may persist and worsen; early multidisciplinary treatment improves long-term outcomes.

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